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[title] => Hoćemo li se morati cijepiti i trećom dozom cjepiva protiv COVID-a? Markotić: ‘Vrlo je moguće da će pred zimu trebati još jedno docjepljivanje‘
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Pokazalo se da su mRNK-a cjepiva kao što su Pfizer-BioNTech i Moderna, u dvije doze efikasna 95 posto, no znanstvenici koji su pomogli njihovom razvoju kažu kako uočavaju da tako jaka zaštita na COVID-19 s vremenom opada. U svijetu se, stoga sve više raspravlja hoće li biti potrebe za docjepljivanjem i trećom dozom cjepiva.
„Vrlo je moguće da će se negdje pred zimu trebati još jedno docjepljivanje, moguće je da će biti situacija kao s gripom – da ćemo svake godine trebati određeno docjepljivanje i tu čekamo neke nove, relevantne podatke, napominje prof. dr. Alemka Markotić, ravnateljica Klinike za infektivne bolesti „Dr. Fran Mihaljević“.
Vodeći stručnjaci Pfizera u nekoliko su navrata izjavili da će ljudi vjerojatno trebati dodatnu injekciju ili treću dozu cjepiva u roku od 12 mjeseci od potpunog cijepljenja i to posebice zbog pojave novih varijanti koronavirusa.
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I britanski se znanstvenici već duže vrijeme pripremaju za uvođenje treće doze, no kako je izjavio ministar Nadhim Zahawi konačnu odluku o tome još nisu donijeli. Britanija je druga u svijetu država po brzini procjepljivanja stanovništva protiv koronavirusa te je prvu dozu primila polovica odrasle populacije. Vlada sada razmišlja o trećoj dozi kojom bi se cijepile starije i ranjive skupine najesen nakon što svo odraslo stanovništvo primi drugu dozu.
Kod nas još ima dosta posla oko cijepljenja s prvom i drugom dozom, i ono što sad ima Velika Britanija, mi ne možemo postići u bliskoj budućnosti. No, ipak se razmišlja i o trećoj dozi pogotovo za one koji su prvi cijepljeni i spadaju u najosjetljivije skupine.
- Spremam se provesti istraživanje u kojemu ćemo izmjeriti razinu protutijela u osoba koje su cijepljene u domovima za starije i potom promatrati razinu antitijela u krvi nakon šest mjeseci od cijepljenja, pa opet nakon devet mjeseci kako bi ustanovili je li im se i koliko smanjio zaštitni titar.
Ako se pokaže da im protutijela padaju to bi onda bio razlog da ih se na jesen cijepi dodatnom, trećom dozom – kaže nam prof. dr. Branko Kolarić, epidemiolog i voditelj Referentnog centra Ministarstva zdravstva za zaštitu zdravlja starijih osoba.
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„Zasad mi u Hrvatskoj iz naših primjera ne znamo koliko zaštita od cijepljenja traje jer nemamo još ljudi koji su cijepljeni prije više od šest mjeseci. Jedine spoznaje koje imamo su ove iz kliničkih istraživanja kod ljudi koji su cijepljeni još prošlo ljeto. Oni još imaju protutijela, no vidjet ćemo koliko će ih imati nakon godinu dana i na osnovu toga ćemo moći odlučiti je li potrebna dodatna doza – naglašava prof. Kolarić.
Treća doza može biti ista ili različita od sadašnjeg cjepiva, ovisno o varijanti koja će u nekom trenutku prevladavati u epidemiji. Trenutno je to britanski soj.
Tvrtka Moderna Inc. objavila je ovaj tjedan prve podatke istraživanja koje pokazuje da treća doza sadašnjeg ili eksperimentalnog novog kandidata za cjepivo osnažuje imuni odgovor na brazilsku i južnoafričku varijantu koronavirusa.
Docjepljivanje trećom dozom, koje je dano dobrovoljcima ranije cijepljenima Modernom u dvije doze, pojačalo je odgovor antitijela i na izvornu verziju koronavirusa koja izaziva covid-19. Prvi podaci rezultat su testiranja na 40 dobrovoljaca sadašnjeg Modernina cjepiva, kao i verzije cjepiva koje tvrtka razvija kao odgovor na novu južnoafričku varijantu koronavirusa. Moderna također proučava cijepljenje koje kombinira sadašnje i novo cjepivo.
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Pokazalo se da su mRNK-a cjepiva kao što su Pfizer-BioNTech i Moderna, u dvije doze efikasna 95 posto, no znanstvenici koji su pomogli njihovom razvoju kažu kako uočavaju da tako jaka zaštita na COVID-19 s vremenom opada. U svijetu se, stoga sve više raspravlja hoće li biti potrebe za docjepljivanjem i trećom dozom cjepiva.
„Vrlo je moguće da će se negdje pred zimu trebati još jedno docjepljivanje, moguće je da će biti situacija kao s gripom – da ćemo svake godine trebati određeno docjepljivanje i tu čekamo neke nove, relevantne podatke, napominje prof. dr. Alemka Markotić, ravnateljica Klinike za infektivne bolesti „Dr. Fran Mihaljević“.
Vodeći stručnjaci Pfizera u nekoliko su navrata izjavili da će ljudi vjerojatno trebati dodatnu injekciju ili treću dozu cjepiva u roku od 12 mjeseci od potpunog cijepljenja i to posebice zbog pojave novih varijanti koronavirusa.
---
---
I britanski se znanstvenici već duže vrijeme pripremaju za uvođenje treće doze, no kako je izjavio ministar Nadhim Zahawi konačnu odluku o tome još nisu donijeli. Britanija je druga u svijetu država po brzini procjepljivanja stanovništva protiv koronavirusa te je prvu dozu primila polovica odrasle populacije. Vlada sada razmišlja o trećoj dozi kojom bi se cijepile starije i ranjive skupine najesen nakon što svo odraslo stanovništvo primi drugu dozu.
Kod nas još ima dosta posla oko cijepljenja s prvom i drugom dozom, i ono što sad ima Velika Britanija, mi ne možemo postići u bliskoj budućnosti. No, ipak se razmišlja i o trećoj dozi pogotovo za one koji su prvi cijepljeni i spadaju u najosjetljivije skupine.
- Spremam se provesti istraživanje u kojemu ćemo izmjeriti razinu protutijela u osoba koje su cijepljene u domovima za starije i potom promatrati razinu antitijela u krvi nakon šest mjeseci od cijepljenja, pa opet nakon devet mjeseci kako bi ustanovili je li im se i koliko smanjio zaštitni titar.
Ako se pokaže da im protutijela padaju to bi onda bio razlog da ih se na jesen cijepi dodatnom, trećom dozom – kaže nam prof. dr. Branko Kolarić, epidemiolog i voditelj Referentnog centra Ministarstva zdravstva za zaštitu zdravlja starijih osoba.
---
---
„Zasad mi u Hrvatskoj iz naših primjera ne znamo koliko zaštita od cijepljenja traje jer nemamo još ljudi koji su cijepljeni prije više od šest mjeseci. Jedine spoznaje koje imamo su ove iz kliničkih istraživanja kod ljudi koji su cijepljeni još prošlo ljeto. Oni još imaju protutijela, no vidjet ćemo koliko će ih imati nakon godinu dana i na osnovu toga ćemo moći odlučiti je li potrebna dodatna doza – naglašava prof. Kolarić.
Treća doza može biti ista ili različita od sadašnjeg cjepiva, ovisno o varijanti koja će u nekom trenutku prevladavati u epidemiji. Trenutno je to britanski soj.
Tvrtka Moderna Inc. objavila je ovaj tjedan prve podatke istraživanja koje pokazuje da treća doza sadašnjeg ili eksperimentalnog novog kandidata za cjepivo osnažuje imuni odgovor na brazilsku i južnoafričku varijantu koronavirusa.
Docjepljivanje trećom dozom, koje je dano dobrovoljcima ranije cijepljenima Modernom u dvije doze, pojačalo je odgovor antitijela i na izvornu verziju koronavirusa koja izaziva covid-19. Prvi podaci rezultat su testiranja na 40 dobrovoljaca sadašnjeg Modernina cjepiva, kao i verzije cjepiva koje tvrtka razvija kao odgovor na novu južnoafričku varijantu koronavirusa. Moderna također proučava cijepljenje koje kombinira sadašnje i novo cjepivo.
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11. svibanj 2024 15:21
